mutation

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Patrick Haggard

Voluntary Action

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David Adger

The Nature of Language

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Gareth Jones

Undecidable Problems

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David Adger

Language and Artificial Intelligence

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Steve Jones

Genes and the Environment

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Onur Güntürkün

Self-construction

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Anson Mackay

Fresh Water and Climate Change

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Erol Gelenbe

Cloud Computing

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John Ellis

Mutations in Humans

Evolutionary biologist Armand Leroi on the ways to understand the functions of all human genes, Cyclopia or holoprosencephaly and what is physical beauty

Huntington’s Disease

Molecular Neurogeneticist David Rubinsztein on the Kennedy disease, CAG repeats, and autophagy

Identifying Adaptive Mutations

Biologist Hopi Hoekstra on sand dunes of Nebraska, agouti signaling protein, and adaptation to the habitat

Driver and Passenger Mutation in Cancer

Biophysicist Leonid Mirny on mutation balance, vulnerability of cancer, and its new explanatory paradigm

Somatic Mutation Rate and Cancer Genes

Harvard Associate Prof. Shamil Sunyaev on imaginative biochemistry, identifying oncogenes, and nucleotide excision repair

Mitochondrial Genetics of Aging

Associate Prof. Konstantin Khrapko of Harvard University on mutations in non-nuclear DNA, substantia nigra, and aging of Drosophila's intestine

Mutation, Selection and Genetic Drift

Biologist Shamil Sunyaev on the sources of genetic variance, reconstructing population history, and disease risk

Engineering More Effective Antibiotics

Boston University Prof. James Collins on bacterial resistance, active mutagens, and efficacy of biocides

Genetics of Color Adaptation

Prof. Hopi Hoekstra of Harvard University on beneficial mutations, wild mice as a model system, and patterns of genetic variation

Predicting Functional Effect of Human Mutations

Harvard Associate Prof. Shamil Sunyaev on protein evolution model, human disease mutations, and the help of different vertebrate species for human genetic research

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